Seventy-two hour survival curves in the mouse (A) and rat (B) models of sepsis. Clinical severity was scored for each animal at 6 and 24 h using a previously published scoring system (5). The average score (± SEM) for mildly (C) and severely septic (D) animals is shown. Sham mice scored 0 at both time points. *p < 0.01 one-way ANOVA and §p < 0.01 (ANOVA), comparing mild and severe to the sham group in rats at 6 h.