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Intensive Care Medicine Experimental

Table 2 Temperature, metabolic and echocardiography data in severely septic mice

From: The metabolic phenotype of rodent sepsis: cause for concern?

 

Baseline

10-h

24-h

 

Pre-rewarming

Post-rewarming

Pre-rewarming

Post-rewarming

Temperature (°C)

36.1 ± 0.2

30.0 ± 1.5*

36.3 ± 0.6**

28.8 ± 2.1*

36.6 ± 1.7

VO2 (ml/kg/h)

2,288 ± 181

925 ± 131*

1,190 ± 131**

730 ± 90*

941 ± 178

Peak velocity (m/s)

1.06 ± 0.06

0.46 ± 0.08*

0.80 ± 0.10**

0.66 ± 0.07*

1.14 ± 0.13

Heart rate (beats/min)

509 ± 31

452 ± 23

601 ± 45**

435 ± 6

614 ± 47

Stroke volume (μl)

60 ± 3

21 ± 3*

32 ± 6**

36 ± 4*

52 ± 11

  1. Data were taken from severely septic mice at baseline (0 h) and before and after rewarming at 10 h (6 mice) and 24 h (3 mice). Rewarming took place over 1.5 h. Mice were only anaesthetized for the period of echocardiography. Values denote mean ± standard deviation. *p < 0.05 paired t test comparing the values to corresponding baseline (0 h) values. **p < 0.05 paired t test comparing post-warming values to their corresponding pre-warming value.
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