TY - JOUR AU - Richard, Jean-Christophe AU - Pouzot, Céline AU - Pinzón, Alfredo Morales AU - González, Juan Sebastian Torres AU - Orkisz, Maciej AU - Neyran, Bruno AU - Hoyos, Marcela Hernández AU - Lavenne, Franck AU - Guerin, Claude PY - 2014 DA - 2014/04/09 TI - Reliability of the nitrogen washin-washout technique to assess end-expiratory lung volume at variable PEEP and tidal volumes JO - Intensive Care Medicine Experimental SP - 10 VL - 2 IS - 1 AB - End-expiratory lung volume measurement by the nitrogen washin-washout technique (EELVWI-WO) may help titrating positive end-expiratory pressure (PEEP) during acute respiratory distress syndrome (ARDS). Validation of this technique has been previously performed using computed tomography (EELVCT), but at mild PEEP levels, and relatively low fraction of inspired oxygen (FiO2), which may have insufficiently challenged the validity of this technique. The aims of this study were (1) to evaluate the reliability of EELVWI-WO measurements at different PEEP and VT during experimental ARDS and (2) to evaluate trending ability of EELVWI-WO to detect EELV changes over time. SN - 2197-425X UR - https://doi.org/10.1186/2197-425X-2-10 DO - 10.1186/2197-425X-2-10 ID - Richard2014 ER -