ΔEELVCTthreshold for AUC computation (mL)
|
AUC (CI 95%)
|
Optimal ΔEELVWI-WOcut-off (mL)
|
Se
|
Sp
|
PPV
|
NPV
|
PLR
|
NLR
|
Youden index
|
---|
100
|
0.58 (0.50 to 0.66)
|
42
|
0.84
|
0.33
|
0.57
|
0.66
|
1.25
|
0.48
|
0.17
|
150
|
0.73 (0.64 to 0.81)
|
166
|
0.65
|
0.75
|
0.46
|
0.87
|
2.61
|
0.47
|
0.40
|
200
|
0.79 (0.70 to 0.89)
|
166
|
0.80
|
0.75
|
0.42
|
0.94
|
3.26
|
0.27
|
0.55
|
250
|
0.87 (0.79 to 0.94)
|
169
|
0.90
|
0.77
|
0.41
|
0.97
|
3.89
|
0.13
|
0.67
|
300
|
0.89 (0.83 to 0.95)
|
169
|
0.93
|
0.77
|
0.41
|
0.98
|
4.05
|
0.09
|
0.70
|
- AUC, area under receiver operating characteristic curve; CI 95%, 95% confidence interval; ΔEELV
CT
, absolute change in end-expiratory lung volume assessed by computed tomography between consecutive time points; ΔEELV
WI-WO
, absolute change in end-expiratory lung volume assessed with the nitrogen washin-washout technique between consecutive time points; NLR, negative likehood ratio; NPV, negative predictive value; PLR, positive likehood ratio; PPV, positive predictive value; Se, sensitivity, Sp, specificity.