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Figure 1 | Intensive Care Medicine Experimental

Figure 1

From: A standardized model of brain death, donor treatment, and lung transplantation for studies on organ preservation and reconditioning

Figure 1

Schematic overview of the experiment flow. Each experiment was run using two animals (lung donor and transplantation recipient). The donor underwent induction of brain death followed by organ donor management for a total of 9 h after brain death induction (BD); the lungs were then harvested and cold-stored for 8 h (Ischemia). The recipient pig underwent pneumonectomy and transplantation of the left donor lung, post-reperfusion follow-up was carried on for the following 6 hours (Graft). Arrows in the figure represent the following timings: BD refers to the end of donor management; Ischemia indicates the end of 8 h of cold storage and Graft the end of 6 h follow-up after graft reperfusion.

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