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Table 2 Recipient parameters

From: A standardized model of brain death, donor treatment, and lung transplantation for studies on organ preservation and reconditioning

 

Baseline

Reperfusion

1 h

4 h

6 h

P value

Temperature, °C

37.2 ± 0.8

37.9 ± 0.6

38.0 ± 0.9

37.9 ± 1.2

38.2 ± 1.2

0.153

Heart rate, beats/min

102 ± 24

103 ± 24

102 ± 28

105 ± 19

104 ± 4

0.891

Mean arterial pressure, mmHg

114 ± 19

99 ± 20

91 ± 21

80 ± 6a

76 ± 10a

<0.05

Pulmonary artery pressure, mmHg

23 ± 5

25 ± 4

25 ± 3

24 ± 4

26 ± 4

0.424

Central venous pressure, mmHg

9 ± 4

6 ± 2

8 ± 3

8 ± 1

9 ± 2

0.105

Cardiac output, L/min

3.6 ± 0.4

4.2 ± 1.2

3.3 ± 0.4

3.3 ± 0.7

3.1 ± 0.6b

<0.05

Systemic vascular resistance, dyn · s · cm−5

2,433 ± 396

1,877 ± 681

2,101 ± 763

1,787 ± 427

1,766 ± 407

0.183

Stroke volume variation, %

10 ± 4

6 ± 2

6 ± 1

9 ± 5

9 ± 4

0.385

Global end diastolic volume, mL

464 ± 57

436 ± 134

386 ± 51

456 ± 115

414 ± 109

0.890

Urine output, mL · Kg/h

4.3 ± 3.0

3.1 ± 0.7

4.9 ± 3.0

3.6 ± 2.2

2.0 ± 0.7

0.104

Lactate, mmol/L

1.2 ± 0.4

0.7 ± 0.1

1.0 ± 0.6

0.8 ± 0.2

0.8 ± 0.1

0.382

Oxygen delivery, mL/min

473 ± 65

628 ± 199

459 ± 61

428 ± 90b

385 ± 81b

<0.05

Respiratory rate, breaths/min

18 ± 0

19 ± 4

19 ± 2

17 ± 4

17 ± 4

0.825

Tidal volume, mL

331 ± 47

295 ± 42

321 ± 99

363 ± 136

343 ± 116

0.393

Peak airway pressure, cmH2O

17 ± 1

20 ± 5

20 ± 3

21 ± 4

22 ± 5

0.157

Plateau airway pressure, cmH2O

11 ± 1

12 ± 2

15 ± 0

17 ± 3a

16 ± 4

<0.05

Mean airway pressure, cmH2O

8 ± 0

9 ± 1

12 ± 2ab

13 ± 2ab

12 ± 2ab

<0.05

Positive end-expiratory pressure, cmH2O

5 ± 0

6 ± 2

8 ± 1ab

9 ± 1ab

9 ± 2ab

<0.05

End-tidal CO2, mmHg

47.7 ± 5.2

55.4 ± 7.2

56.6 ± 4.5

49.0 ± 8.7

52.5 ± 6.2

0.096

PaCO2, mmHg

46.6 ± 5.2

52.0 ± 5.0

51.6 ± 8.4

41.2 ± 6.7

49.0 ± 11.3

0.053

pH

7.399 ± 0.029

7.349 ± 0.054

7.383 ± 0.057

7.456 ± 0.060b

7.403 ± 0.086

<0.05

Glucose, g/dL

161 ± 52

134 ± 70

112 ± 59

119 ± 32

124 ± 24

0.168

Na+, mEq/L

138.2 ± 0.8

140.3 ± 4.0

141.8 ± 3.5

140.2 ± 4.6

140.7 ± 4.5

0.226

K+, mEq/L

3.8 ± 0.1

4.7 ± 0.3

4.8 ± 0.8a

5.3 ± 0.7a

5.1 ± 0.7a

<0.05

Ca++, mEq/L

1.32 ± 0.07

1.20 ± 0.06b

1.23 ± 0.07a

1.16 ± 0.08abc

1.15 ± 0.07abc

<0.05

Cl−, mEq/L

98.8 ± 3.6

99.3 ± 2.1

101.0 ± 3.5

101.0 ± 3.7

101.0 ± 5.4

0.829

Na+urinary, mEq/L

49.4 ± 19.9

-

-

60.5 ± 40.3

-

0.475

K+urinary, mEq/L

38.1 ± 21.4

-

-

95.9 ± 46.8

-

0.053

pHurinary

6.801 ± 0.843

-

-

6.702 ± 0.978

-

0.875

  1. Table 2 shows respiratory, hemodynamic, and metabolic parameters and urinary electrolytes of recipient pigs collected after surgery (Baseline), at the beginning of reperfusion (Reperfusion) and after 1, 4, and 6 h after reperfusion. Data are presented as mean ± standard deviation. One-way ANOVA repeated measures. P < 0.05 accepted as significant: avs. Baseline, bvs. Reperfusion, and cvs. 1 h.