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Table 2 Recipient parameters

From: A standardized model of brain death, donor treatment, and lung transplantation for studies on organ preservation and reconditioning

  Baseline Reperfusion 1 h 4 h 6 h P value
Temperature, °C 37.2 ± 0.8 37.9 ± 0.6 38.0 ± 0.9 37.9 ± 1.2 38.2 ± 1.2 0.153
Heart rate, beats/min 102 ± 24 103 ± 24 102 ± 28 105 ± 19 104 ± 4 0.891
Mean arterial pressure, mmHg 114 ± 19 99 ± 20 91 ± 21 80 ± 6a 76 ± 10a <0.05
Pulmonary artery pressure, mmHg 23 ± 5 25 ± 4 25 ± 3 24 ± 4 26 ± 4 0.424
Central venous pressure, mmHg 9 ± 4 6 ± 2 8 ± 3 8 ± 1 9 ± 2 0.105
Cardiac output, L/min 3.6 ± 0.4 4.2 ± 1.2 3.3 ± 0.4 3.3 ± 0.7 3.1 ± 0.6b <0.05
Systemic vascular resistance, dyn · s · cm−5 2,433 ± 396 1,877 ± 681 2,101 ± 763 1,787 ± 427 1,766 ± 407 0.183
Stroke volume variation, % 10 ± 4 6 ± 2 6 ± 1 9 ± 5 9 ± 4 0.385
Global end diastolic volume, mL 464 ± 57 436 ± 134 386 ± 51 456 ± 115 414 ± 109 0.890
Urine output, mL · Kg/h 4.3 ± 3.0 3.1 ± 0.7 4.9 ± 3.0 3.6 ± 2.2 2.0 ± 0.7 0.104
Lactate, mmol/L 1.2 ± 0.4 0.7 ± 0.1 1.0 ± 0.6 0.8 ± 0.2 0.8 ± 0.1 0.382
Oxygen delivery, mL/min 473 ± 65 628 ± 199 459 ± 61 428 ± 90b 385 ± 81b <0.05
Respiratory rate, breaths/min 18 ± 0 19 ± 4 19 ± 2 17 ± 4 17 ± 4 0.825
Tidal volume, mL 331 ± 47 295 ± 42 321 ± 99 363 ± 136 343 ± 116 0.393
Peak airway pressure, cmH2O 17 ± 1 20 ± 5 20 ± 3 21 ± 4 22 ± 5 0.157
Plateau airway pressure, cmH2O 11 ± 1 12 ± 2 15 ± 0 17 ± 3a 16 ± 4 <0.05
Mean airway pressure, cmH2O 8 ± 0 9 ± 1 12 ± 2ab 13 ± 2ab 12 ± 2ab <0.05
Positive end-expiratory pressure, cmH2O 5 ± 0 6 ± 2 8 ± 1ab 9 ± 1ab 9 ± 2ab <0.05
End-tidal CO2, mmHg 47.7 ± 5.2 55.4 ± 7.2 56.6 ± 4.5 49.0 ± 8.7 52.5 ± 6.2 0.096
PaCO2, mmHg 46.6 ± 5.2 52.0 ± 5.0 51.6 ± 8.4 41.2 ± 6.7 49.0 ± 11.3 0.053
pH 7.399 ± 0.029 7.349 ± 0.054 7.383 ± 0.057 7.456 ± 0.060b 7.403 ± 0.086 <0.05
Glucose, g/dL 161 ± 52 134 ± 70 112 ± 59 119 ± 32 124 ± 24 0.168
Na+, mEq/L 138.2 ± 0.8 140.3 ± 4.0 141.8 ± 3.5 140.2 ± 4.6 140.7 ± 4.5 0.226
K+, mEq/L 3.8 ± 0.1 4.7 ± 0.3 4.8 ± 0.8a 5.3 ± 0.7a 5.1 ± 0.7a <0.05
Ca++, mEq/L 1.32 ± 0.07 1.20 ± 0.06b 1.23 ± 0.07a 1.16 ± 0.08abc 1.15 ± 0.07abc <0.05
Cl, mEq/L 98.8 ± 3.6 99.3 ± 2.1 101.0 ± 3.5 101.0 ± 3.7 101.0 ± 5.4 0.829
Na+urinary, mEq/L 49.4 ± 19.9 - - 60.5 ± 40.3 - 0.475
K+urinary, mEq/L 38.1 ± 21.4 - - 95.9 ± 46.8 - 0.053
pHurinary 6.801 ± 0.843 - - 6.702 ± 0.978 - 0.875
  1. Table 2 shows respiratory, hemodynamic, and metabolic parameters and urinary electrolytes of recipient pigs collected after surgery (Baseline), at the beginning of reperfusion (Reperfusion) and after 1, 4, and 6 h after reperfusion. Data are presented as mean ± standard deviation. One-way ANOVA repeated measures. P < 0.05 accepted as significant: avs. Baseline, bvs. Reperfusion, and cvs. 1 h.