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Table 3 Lung function parameters

From: A standardized model of brain death, donor treatment, and lung transplantation for studies on organ preservation and reconditioning

  Donor Recipient
Baseline Before procurement After reperfusion P value
PaO2/FiO2, mmHg 540 ± 32 480 ± 31 532 ± 19 0.564
Elastance of respiratory system, cmH2O/L 20.5 ± 7.9 18.4 ± 7.7 22.6 ± 6.9 0.687
Elastance of lung, cmH2O/L 12.9 ± 5.2 15.3 ± 7.7 15.3 ± 7.0 0.846
End expiratory lung volume, mL 735 ± 187 803 ± 312 749 ± 213 0.900
Physiologic dead space fraction 0.54 ± 0.03 0.51 ± 0.07 0.49 ± 0.08 0.631
End-tidal CO2/PaCO2 1.06 ± 0.04 1.13 ± 0.09 1.19 ± 0.08 0.133
Extravascular lung water, mL 359 ± 79 359 ± 80 366 ± 117 0.949
Wet/dry ratio 6.2 ± 7.0 5.8 ± 0.5 5.6 ± 0.6 0.629
  1. Table 3 shows functional lung parameters in the donor and recipient animals. ‘Before procurement’ refers to data taken at the end the donation process at the time of lung procurement, except for wet-to-dry ratio that was measured in sham-operated animals. BD refers to data taken at the end of donor management; ‘After reperfusion’ refers to data taken at the end of post-reperfusion follow-up. Oxygenation of the implanted lung (After reperfusion, n = 3) was assessed by selective left pulmonary vein blood gas analysis. Data are presented as mean ± standard deviation. One-way ANOVA. P < 0.05 accepted as significant.