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Intensive Care Medicine Experimental

Table 2 EELV and inhomogeneity index parameters during different levels of PEEP before and after ALI

From: Assessment of ventilation inhomogeneity during mechanical ventilation using a rapid-response oxygen sensor-based oxygen washout method

 

PEEP (cm H2O)

 

Before acute lung injury

After acute lung injury

 

15

10

5

0

15

10

5

0α

EELV (mL)

1,458

1,064*

720*

400*

848*

446*

238*

182*

Lung clearance index

6.1

6.3

6.4*

7.3*

7.2

9.8*

12.9*

19.7

Mixing ratio

1.2

1.2

1.2

1.1

1.2

1.3

1.5*

1.4

Becklake index

4.2

4.2

4.5

5.6*

4.9

6.7*

11.7*

19.3

MBAMI (%)

13.6

12.9

14.8

20.6

15.6

25.8*

45.2*

39.5

Moment ratio

1.6

1.7

1.7*

2.0*

2.0

2.4*

2.9*

3.9

Pulmonary clearance delay (%)

14.7

13.0

10.6

10.0*

15.9

17.4

20.2

10.3

  1. Values are expressed as means. *p < 0.05, significance compared to PEEP 15 (Wilcoxon matched-pairs test), α; n = 6 (unable to perform measurements in two piglets).
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