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Intensive Care Medicine Experimental

Table 3 EELV and inhomogeneity index parameters before and after induction of lung injury during baseline

From: Assessment of ventilation inhomogeneity during mechanical ventilation using a rapid-response oxygen sensor-based oxygen washout method

 

Before acute lung injury

After acute lung injury

Mean variation coefficient %

N2washout in normal subjects[11]

 

(n = 7)

(n = 7)

  

EELV (mL)

537 (127)

159 (55)**

5.2

 

Lung clearance index

6.7 (0.6)

12.7 (4.3)**

10.4

7.1 (1.3)

Mixing ratio

1.2 (0.1)

1.3 (0.1)

7.8

1.57 (0.22)

Becklake index

4.6 (0.5)

11.2 (4.5)**

11.3

3.7 (0.8)

MBAMI (%)

14.6 (6.0)

35.8 (19.4)*

33.5

25 (10)

Moment ratio

1.8 (0.1)

3.0 (0.5)*

5.6

2.02 (0.14)

Pulmonary clearance delay mean (%)

11.0 (4.2)

13.7 (7.8)

29.3

31 (25)

Slope phase 3 capnogram (kPa/L)

2.1 (1.2)

7.0 (3.7)*

  
  1. All measurements were performed at 5 cm H2O of PEEP. Capnogram values are averaged over 100 successive breaths and increased significantly after induction of ALI. Values are expressed as mean (SD). *p < 0.05; **p < 0.01 (Wilcoxon matched-pairs test).
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