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Figure 3 | Intensive Care Medicine Experimental

Figure 3

From: Genetic and pharmacologic inhibition of Tpl2 kinase is protective in a mouse model of ventilator-induced lung injury

Figure 3

Oxygenation. Arterial blood gas PaO2 from wild-type (WT, white boxes), and Tpl2-deficient mice (Tpl2-/-, gray boxes) subjected to mechanical ventilation with normal tidal volume (VT) for 240 min, or high VT for 210 min (n = 6 to 8 per group). PaO2 was lower in WT mice subjected to high VT than in similarly ventilated Tpl2-/-mice, *p < 0.05.

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