Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 Parameters of macro- and microcirculatory hemodynamics, blood gases, and acid-base status

From: Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock

  Hyperglycemia Normoglycemia
Vehicle EMD008 Vehicle EMD008
Heart rate (beats · min-1) Start 422 (375;510) 446 (379;481) 459 (406;509) 351 (365;392)
End 452 (420;489) 437 (390;456) 495 (478;505) 352 (350;384)
Mean arterial pressure (mmHg) Start 62 (60;67) 65 (60;67) 61 (59;67) 71 (64;74)
End 60 (57;64) 58 (53;64) 62 (58;65) 67 (65;75)
Portal venous flow (mL · min-1) Start 5.2 (4.3;8.0) 7.2 (5.6;7.8) 9.4 (7.9;11.6) 5.8 (4.5;7.0)
End 5.1 (4.0;6.1) 6.2 (5.4;6.8) 8.9 (8.0;11.8) 5.3 (4.2;6.5)
Liver μ-vascular flow (AU) Start 132 (121;142) 136 (121;160) 135 (118;180) 140 (124;159)
End 124 (105;141) 118 (111;130) 106 (87;115) 111 (101;124)
Liver μ-Hb O2 saturation (%) Start 65 (63;67) 71 (66;73) 67 (63;72) 66 (63;74)
End 65 (63;69) 67 (64;71) 64 (59;65) 67 (62;71)
Arterial PO2 (mmHg) Start 336 (311;363) 350 (345;364) 368 (360;379) 347 (340;354)
End 314 (277;-334) 344 (324;350) 312 (301;322) 328 (323;340)
Arterial PCO2 (mmHg) Start 34 (26;35) 30 (29;33) 28 (27;30) 31 (28;33)
End 35 (32;38) 40 (35;43) 29 (28;31) 30 (29;34)
Arterial pH Start 7.34 (7.31;7.36) 7.32 (7.29;7.36) 7.36 (7.31;7.40) 7.39 (7.33;7.40)
  End 7.31 (7.26;7.33)$ 7.20 (7.02;7.30)$ 7.30 (7.25;7.33)$ 7.40 (7.32;7.41)
Arterial base excess (mmol · L-1) Start -9.2 (-11.0;-6.3) -9.2 (-9.6;-8.4) -10.0 (-10.3;-7.0) -7.2 (-9.3;-7.0)
  End -9.3 (-10.5;-4.6) -13.1 (-17.2;-9.3)$ -11.4 (-12.6;-9.5)$ -7.6 (-9.1;-6.4)
  1. Liver μ-vascular flow and μ-Hb O2 saturation are capillary blood flow and hemoglobin O2 saturation, respectively. All data are median (quartiles); $p < 0.05 start vs. end within one group.