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Table 3 Signal transduction and mediator proteins

From: Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock

  Hyperglycemia Normoglycemia
Vehicle EMD008 Vehicle EMD008
Tail moment 0.5 (0.5;0.6) 0.6 (0.5;0.7) 0.5 (0.4;0.6) 0.6 (0.4;0.7)
HO-1 1.6 (1.6;1.7) 2.2 (2.0;2.3)§ 1.7 (1.6;1.8) 1.9 (1.6;2.2)
Bax 1.7 (1.5;1.9)# 1.3 (1.3;1.3)§ 1.3 (1.1;1.3) 1.3 (1.3;1.4)
Caspase-3 1.1 (1.1;1.2) 1.0 (0.9;1.1) 1.1 (1.0;1.3) 0.7 (0.7;0.8)§
AMPK activation 0.6 (0.6-0.7)# 0.8 (0.8;0.9)§ 0.8 (0.8;0.9) 0.8 (0.7;0.8)
Total AMPK 1.0 (0.99;1.05) 1.03 (0.98;1.08) 1.0 (0.98;1.02) 1.06 (0.99-1.08)
  1. AMPK activation is expressed as TH172-phosphorylated AMPK in percentage of total AMPK. All values are expressed as fold over control values from animals that had not undergone surgery. All data are median (quartiles). #p < 0.05 vs. normoglycemia; §p < 0.05 vs. vehicle.