Roger [43]
|
Sepsis
|
48
|
Healthy volunteer
|
15
|
Pathophysiological
|
No
|
Bandyopadhyay [58]
|
Trauma
|
113
|
Healthy volunteer
|
?
|
Pathophysiological
|
No
|
White [11]
|
Sepsis
|
60
|
Gram negative infection and healthy volunteer
|
15 and 20
|
Pathophysiological
|
Yes
|
White [11]
|
Elective surgery (infective complications)
|
19
|
Cohort
|
41
|
“
|
“
|
Zhang [44]
|
Sepsis
|
19
|
Healthy volunteer
|
22
|
Pathophysiological
|
No
|
Guignant [45]
|
Sepsis
|
64
|
Healthy volunteer
|
49
|
Pathophysiological
|
No
|
Vaki [46]
|
Sepsis
|
48 (68)
|
Healthy volunteer
|
20
|
Pathophysiological
|
No
|
Slotwinski [62]
|
Elective surgery
|
50 (26, 24)
|
Cohort
|
50
|
Experimental/clinical outcome
|
No
|
Gogos [47]
|
Sepsis
|
PN 183, CAP 97, IA 100, PB 61, HAP 64
|
N/A
| |
Pathophysiological
|
Yes
|
Hoogerwerf [48]
|
Sepsis
|
16
|
Healthy volunteer
|
24
|
Pathophysiological
|
No
|
Yousef [49]
|
Sepsis
|
32
|
SIRS and without SIRS
|
35/33
|
Patient outcome
|
Yes
|
Turrel-Davin [50]
|
Sepsis
|
13
|
Healthy volunteer
|
15
|
Biomarker comparison
|
No
|
Pelekanou [51]
|
Sepsis
|
VAP 36
|
Other infections
|
32
|
Pathophysiology
|
No
|
Papadima [61]
|
Elective surgery
|
40 (21, 19)
|
Cohort
|
40
|
Pathophysiological
|
No
|
Delogu [52]
|
Sepsis
|
16
|
?‘individuals’
| |
Pathophysiological
|
No
|
Weber [53]
|
Sepsis
|
16
|
Non-infected ICU and healthy volunteer
|
10 and 11
|
Pathophysiological
|
No
|
Roth [54]
|
Sepsis
|
15
|
Healthy volunteer
|
20
|
Pathophysiological
|
No
|
Le Tulzo [55]
|
Sepsis
|
47 (25, 23)
|
SIRS and healthy volunteer
|
7 and 25
|
Pathophysiological/clinical outcome
|
Yes
|
Hotchkiss [56]
|
Sepsis
|
27 (FC 5) (3 intraop, 24 autopsy)
|
Critically ill non-septic and trauma
|
16 and 25 (FC 6) (3 prospective, 13 retrospective)
|
Pathophysiological
|
No
|
Delogu [63]
|
Elective surgery
|
18
|
Cohort
|
18
|
Pathophysiological
|
No
|
Pellegrini [59]
|
Trauma
|
17 (+13 burns)
|
Healthy volunteer
|
17
|
Clinical outcome/pathophysiological
|
(Correlate to MODS)
|
Delogu [64]
|
Surgical
|
15
|
Healthy volunteer
|
10
|
Pathophysiological/patient outcome
|
Yes
|
Hotchkiss [60]
|
Trauma
|
10
|
Elective surgery
|
6 (all prospective)
|
Pathophysiological
|
No
|
Hotchkiss [57]
|
Sepsis
|
20
|
Non septic prospective/non-septic retrospective/prospective trauma splenectomy/ prospective colectomy/retrospective colectomy
|
1/9/6/2/8
|
Pathophysiological
|
No
|
Sasajima [65]
|
Elective surgery
|
16 (11, 5)
|
Cohort
|
16
|
Pathophysiological
|
No
|
Sugimoto [66]
|
Elective surgery
|
10 (5, 5)
|
Cohort
|
10
|
Pathophysiological
|
No
|