Skip to main content

Table 1 Gas exchange in an animal model of LPS–induced lung; ventilated with heliox or oxygen-in-air

From: Mechanical ventilation with heliox in an animal model of acute respiratory distress syndrome

 

Time (h)

Healthy

 

LPS

 

Oxygen-in-air

Heliox

Oxygen-in-air

Heliox

pH

0

7.44 ± 0.04

7.42 ± 0.03

7.35 ± 0.05a

7.34 ± 0.08b

4

7.33 ± 0.04c

7.36 ± 0.03d

7.30 ± 0.06

7.30 ± 0.08

pCO2 (kPa)

0

4.38 ± 0.7

4.86 ± 0.6

5.78 ± 0.6a

6.10 ± 1.4b

4

4.99 ± 0.4

5.81 ± 0.9

5.84 ± 0.77

5.75 ± 1.29

pO2 (kPa)

0

34.2 ± 1.8

31.7 ± 1.5

33.2 ± 1.7

32.3 ± 3.3

4

31.7 ± 2.5

30.8 ± 2.8

28.5 ± 3.9

28.8 ± 3.4

  1. aOxygen-in-air LPS T = 0 vs. oxygen-in-air healthy T = 0, significant after Bonferroni's multiple comparison test (P < 0.01); bHeliox LPS T = 0 vs. heliox healthy T = 0, significant after Bonferroni's multiple comparison test (P < 0.01); cOxygen-in-air healthy T = 0 vs. oxygen-in-air healthy T = 4, significant after Bonferroni correction (P < 0.0125); dHeliox healthy T = 0 vs. heliox healthy T = 4, significant after Bonferroni correction (P < 0.0125). Data are presented as mean ± SD. N = 8 per group.