Table 1 Histology (day 5)
From: 0356. Effect of the neuroprotective p53-inhibitor pifithrin-µ in a rodent cardiac arrest model
pifithrin (n=11) | control (n=11) | p | |
|---|---|---|---|
Number of pyknotic cells in CA1 [%; Mean ± SD] | 25 ± 17 | 38 ± 21 | 0.11 |
CA1 cell layer - normalized surface/length [mm2/mm; Median (IQR)] | .060 (.054 - .075) | .053 (.052 - .062) | 0.10 |
Fluoro Jade [numbers of degenerating cells per mm; Mean ± SD] | 94 ± 47 | 128 ± 37 | 0.08 |