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Figure 1 | Intensive Care Medicine Experimental

Figure 1

From: 0593. Reelin mediates the human neutrophil peptide-induced endothelial dysfunction and platelet aggregation

Figure 1

The role of reelin in HNP-induced nitrotyrosine production and platelet aggregation. A. HNP indues reelin (RLN) protein release in HCAEC. Released reelin was determined by western blot from cell culture medium. B. Reelin neutralizing antibody (CR50) reduced HNP-induced nitrotyrosine production. C. CR50 attenuates HNP-stimulated platelet aggregation in ADP-primed human platelet rich plasma. *p<0.05 vs control; §p<0.05 vs HNP 10 μg/mL.

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