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Table 1 Inspiratory flow and incidence of VILI

From: 0990. Role of amplitude and rate of deformation in ventilator-induced lung injury

 

VT 300-400 ml

VT 500-600 ml

VT 750 ml

 

Lower V´

Higher V´

Lower V´

Higher V´

Lower V´

Higher V´

Tidal volume (ml)

338±48

335±42

530±27

520±27

750±0

750±0

Inspiratory flow (ml/sec)

272±36

838±105*

398±21

1278±38*

600±84

1242±95*

Hysteresis (ml*cmH2O)

6260±2236

12938±3356*

11101±4508

34126±4508*

18415±3520

46915±7954*

Incidence of VILI

0/4

1/5

0/5

4/5*

2/5

4/4

  1. Data are presented as mean±standard deviation. * p< 0.05 vs. Lower V' within the same VT group (Student's t, Mann-Whitney Rank Sum or Fisher's exact tests). Hysteresis was associated with incidence of VILI (R=0.68, p< 0.0001) (Spearman Rank Order Correlation).