Serial absolute lactate value < 4 versus relative 10% reduction as a predictor of mortality in severe sepsis and septic shock

Intensive Care Medicine Experimental

Table 2 Comparison based on Lactate Clearance

	Lactate decrease <10%	Lactate decrease > 10%	P-value	Serial Lactate > 4mmol/L	Serial Lactate <4mmol/L	P-value
N	52	109	-	85	76	-
Initial Lactate, mmol/L	6.1	5.9	0.43	6.8	4.9	< 0.0001
Volume Crystalloid in 3 hours, ml	2971.7	2969.4	0.99	2850.5	3080.6	0.39
Vasopressors within 3 hours	22 (42.3)	32 (29.4)	0.11	35 (41.2)	19 (25.0)	0.04
In-hospital Mortality	20 (38.5)	23 (21.1)	0.02	32 (37.7)	11 (14.5)	0.001