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Table 2 Comparison based on Lactate Clearance

From: Serial absolute lactate value < 4 versus relative 10% reduction as a predictor of mortality in severe sepsis and septic shock

  Lactate decrease <10% Lactate decrease > 10% P-value Serial Lactate > 4mmol/L Serial Lactate <4mmol/L P-value
N 52 109 - 85 76 -
Initial Lactate, mmol/L 6.1 5.9 0.43 6.8 4.9 < 0.0001
Volume Crystalloid in 3 hours, ml 2971.7 2969.4 0.99 2850.5 3080.6 0.39
Vasopressors within 3 hours 22 (42.3) 32 (29.4) 0.11 35 (41.2) 19 (25.0) 0.04
In-hospital Mortality 20 (38.5) 23 (21.1) 0.02 32 (37.7) 11 (14.5) 0.001