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Table 1 Css within the first 24-48 hours.

From: Therapeutic drug monitoring of meropenem and piperacilin administered in continuous infusion. preliminary data

antibiotic Cases ƒCss < 4MIC ƒCss 4-10 MIC ƒCss >10 IMC
Meropenem 2 g 14 6 (43%) 7 (50%) 1 (7%)
Piperacilin-tazobactam 16g 15 2 (13 %) 9 (60%) 4 (27%)
Piperacilin-tazobactam 24g 31 11 (35%) 16 (52%) 4 (13%)
Total 60 19 (32%) 32 (53%) 9 (15%)