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Table 1 Css within the first 24-48 hours.

From: Therapeutic drug monitoring of meropenem and piperacilin administered in continuous infusion. preliminary data

antibiotic

Cases

ƒCss < 4MIC

ƒCss 4-10 MIC

ƒCss >10 IMC

Meropenem 2 g

14

6 (43%)

7 (50%)

1 (7%)

Piperacilin-tazobactam 16g

15

2 (13 %)

9 (60%)

4 (27%)

Piperacilin-tazobactam 24g

31

11 (35%)

16 (52%)

4 (13%)

Total

60

19 (32%)

32 (53%)

9 (15%)