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Table 2 Patient characteristics with therapeutic strategy.

From: De-escalation of empiric antibiotic therapy in sepsis - an indian observational study

Variable No change n De-escalation n Escalation n P value
Number of initial empirical antibiotics 1 58 26 32 0.007
Number of initial empirical antibiotics 2 72 26 36  
Number of initial empirical antibiotics 3 18 22 8  
Most Common initial empirical antibiotic beta lactam +beta lactamase inhibitor Carbapenem beta lactam +beta lactamase inhibitor 0.0001
Most Common Escalated /De-escalated Antibiotic beta lactam +beta lactamase inhibitor beta lactam +beta lactamase inhibitor Carbapenem followed by colistin 0.0001
Multi drug resistant organisms 6 8 34 0.0001
ESBL organisms 4 4 10 0.0001
Most Common Source of infection Lung Lung Lung  
H1N1 POSITIVE patients 29 10 6 0.062