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Table 1 Clinical data throughout study time.

From: Development and characterization of a novel model of invasive pneumococcal pneumonia in invasively ventilated PIGS

  Before Bacterial Challenge 24 hours 48 hours 72 hours P-value
Body Temperature (°C) 36.8 ± 0.9 38.7 ± 0.6 38.6 ± 0.8 38.6 ± 0.5 < 0.001
(°C) White Blood Cell (cells/µL) 11,833 ± 4,706 8,237 ± 2,443 19,070 ± 9,229 14,817 ± 7,579 0.042
Platelets (cells/µL) 423,125 ± 104,120 228,625 ± 60,133 164,712 ± 65,953 209,000 ± 71,288 < 0.001
PaO2/FiO2 441.7 ± 62.7 321.1 ± 35.7 288.3 ± 89.9 375.6 ± 52.6 < 0.001
PaCO2 (mmHg) 47.2 ± 6.3 56.0 ± 8.6 41.0 ± 6.0 37.0 ± 5.7 < 0.001
Lung Elastance (cmH2O/L) 14.2 ± 3.2 28.6 ± 16.1 26.5 ± 15.7 26.6 ± 0.5 0.301
Pulmonary Shunt (%) 4.2 ± 2.0 14.8 ± 4.9 13.5 ± 2.9 8.9 ± 3.2 < 0.001
Mean Arterial Pressure (mmHg) 81.2 ± 10.4 68.3 ± 5.4 68.4 ± 3.9 72.9 ± 8.4 0.074
Systemic Vascular Resistance (dynes*sec/cm5) 1857 ± 643 1048 ± 355 1142 ± 377 1419 ± 516 0.014