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Table 1 Patient Demographics for Critically Ill.

From: Hepatocellular response to acute kidney injury in the critically ill: serum induces CYP2D6 transcription

Value - Median [range] Critically Ill, no AKI (n=15) (KDIGO 0) Critically Ill, Severe AKI (n=16) (KDIGO 3)
Age (y) 77 (22-88) 58.5 (19-73)
Sex F:M 7:8 4:12
APACHE II score 20 (5-25) 25 (13-27)
SOFA score 7 (1-11) 7 (3-14)
Baseline Serum Creatinine (umol/L) 85 (58-112) 73 (46-114)
Fold change in Serum Creat from Baseline on study day 0.97 (0.5-1.16) 3.87 (3.1-10.1)
Serum Creatinine when studied (umol/L) 79 (41-131) 304 (157-595)
Cellular Confluence at Harvest (%) 86 (80-90) 85 (80-90)
[Tramadol] ((T4-T0) (ng/mL) [All genotypes included] 23.5 (14.3-39.8) 30.0 (11.7-41.4)