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Table 1 Patient Demographics for Critically Ill.

From: Hepatocellular response to acute kidney injury in the critically ill: serum induces CYP2D6 transcription

Value - Median [range]

Critically Ill, no AKI (n=15) (KDIGO 0)

Critically Ill, Severe AKI (n=16) (KDIGO 3)

Age (y)

77 (22-88)

58.5 (19-73)

Sex F:M

7:8

4:12

APACHE II score

20 (5-25)

25 (13-27)

SOFA score

7 (1-11)

7 (3-14)

Baseline Serum Creatinine (umol/L)

85 (58-112)

73 (46-114)

Fold change in Serum Creat from Baseline on study day

0.97 (0.5-1.16)

3.87 (3.1-10.1)

Serum Creatinine when studied (umol/L)

79 (41-131)

304 (157-595)

Cellular Confluence at Harvest (%)

86 (80-90)

85 (80-90)

[Tramadol] ((T4-T0) (ng/mL) [All genotypes included]

23.5 (14.3-39.8)

30.0 (11.7-41.4)