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Table 1 Patient characteristics.

From: A high anti-inflammatory response is associated with intermediate-term mortality in patients with sepsis

 

Low IL-10 level (n = 148)

Moderate IL-10 level (n = 122)

High IL-10 level (n = 80)

p-value

Age, median (IQR)

65 (56-73)

62 (53-73)

66 (59-73)

0.22

Gender (male), n (%)

94 (64%)

75 (62%)

45 (56%)

0.55

Charlson Comorbidity Index, median (IQR)

4 (0-10)

4 (0-9)

5 (0-11)

0.75

Apache IV score, median (IQR)

82 (67-99)

83 (69-102)

87 (71-113)

0.06

ICU length of stay, median (IQR)

10 (6-17)

10 (7-19)

10 (7-19)

0.38

Total SOFA score day 3, median (IQR)

8 (6-10)

9 (7-11)

10 (8-13)

< 0.01

IL-6 day 4 (pg/ml)*, median (IQR)

3 (2.3-4)

3.9 (3.0-4.7)

4.7 (4-5.5)

< 0.01

Day-14 mortality, n (%)

21 (14%)

11 (9%)

29 (36%)

< 0.01

  1. IQR=Interquartile range. SOFA = Sequential Organ Failure Assessment. Difference between groups (low, moderate, high) was tested by one-way ANOVA or Kruskal-Wallis test for continuous variables as appropriate. Differences between groups for categorical variables was tested for using a Chi-square test. * Log transformed