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Table 2 Matched parameter values and the reference data for the first patient dataset

From: Can computer simulators accurately represent the pathophysiology of individual COPD patients?

No.

Parameter

Data

Model outputs (N = number of compartments)

   

N = 10

N = 25

N = 50

N = 100

1

PaO2 [mm Hg]

125.2

165.29

143.18

133.73

127.92

2

PaCO2 [mm Hg]

46

43.08

44.73

43.62

45.76

3

Dead space fraction

64.9

61.24

62.76

61.28

65.28

4

Shunt fraction

6.8

12.9

9.02

8.07

7.2

5

mean_ V̇

0.99

1

1

1

1

6

mean_Q

0.27

0.2

0.2

0.25

0.2

7

sd_V̇

1

0.92

1.15

0.92

1.15

8

sd_Q

1.34

1.38

1.38

1.38

1.38

9

0.1 < V̇/Q < 1, V̇

19.9

20.43

20.06

22.68

19.94

10

1 < V̇/Q < 10, V̇

14.3

19.69

16.57

16.47

14.48

11

0.01 < V̇/Q < 0.1, P

15.8

22.63

18.86

14.64

16.16

12

0.1< V̇/Q < 1, P

62.1

55.21

58.12

65.57

64.92

13

1 < V̇/Q < 10, P

10.9

11.05

11.58

10.63

10.56

 

Total matching error

 

1.33

0.46

0.11

0.10

 

Simulation time [h]

 

11

32

41

67