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Table 3 Gr oup-averaged data for mean BP, SEP, P1 latencies, and resting LDFV signal

From: Brain function in iNOS knock out or iNOS inhibited (l-NIL) mice under endotoxic shock

  Mean BP (mmHg) SEP (μV) P1 latency (ms) LDFV (U)
Base End Base End Base End Base End (change to baseline)
Control 85 ± 5 73 ± 17 6.6 ± 2.3 5 ± 1.6 9.4 ± 0.5 9.1 ± 0.8 144 ± 30 137 ± 36 (−5%)
Wt + LPS 90 ± 10 56 ± 21* 6.6 ± 3.3 1.2 ± 1.6**** 9.3 ± 0.7 9.4 ± 0.1 153 ± 34 180 ± 40*** (+18%)
Wt + LPS + l-NIL 86 ± 8 68 ± 20 6.8 ± 2.2 3.2 ± 3.3 9.4 ± 0.7 9.3 ± 0.1 151 ± 32 137 ± 45 (−10%)
iNOS(−/−) + LPS 92 ± 15 60 ± 21 7.7 ± 2.2 4.7 ± 3.5 9.5 ± 0.6 9.1 ± 0.9 157 ± 30 130 ± 27 (−17%)
ANOVA ns p < 0.05 ns p < 0.001 ns ns ns p < 0.05
  1. Changes to baseline are also given for the LDFV at the end of experiments. Data are given as mean ± SD together with statistical results. In case of a significant ANOVA, the post hoc statistical test results to baseline are given as *p < 0.05, ***p < 0.005, ****p < 0.0001. No significant differences were seen between sepsis groups.