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Table 3 Gr oup-averaged data for mean BP, SEP, P1 latencies, and resting LDFV signal

From: Brain function in iNOS knock out or iNOS inhibited (l-NIL) mice under endotoxic shock

 

Mean BP (mmHg)

SEP (μV)

P1 latency (ms)

LDFV (U)

Base

End

Base

End

Base

End

Base

End (change to baseline)

Control

85 ± 5

73 ± 17

6.6 ± 2.3

5 ± 1.6

9.4 ± 0.5

9.1 ± 0.8

144 ± 30

137 ± 36 (−5%)

Wt + LPS

90 ± 10

56 ± 21*

6.6 ± 3.3

1.2 ± 1.6****

9.3 ± 0.7

9.4 ± 0.1

153 ± 34

180 ± 40*** (+18%)

Wt + LPS + l-NIL

86 ± 8

68 ± 20

6.8 ± 2.2

3.2 ± 3.3

9.4 ± 0.7

9.3 ± 0.1

151 ± 32

137 ± 45 (−10%)

iNOS(−/−) + LPS

92 ± 15

60 ± 21

7.7 ± 2.2

4.7 ± 3.5

9.5 ± 0.6

9.1 ± 0.9

157 ± 30

130 ± 27 (−17%)

ANOVA

ns

p < 0.05

ns

p < 0.001

ns

ns

ns

p < 0.05

  1. Changes to baseline are also given for the LDFV at the end of experiments. Data are given as mean ± SD together with statistical results. In case of a significant ANOVA, the post hoc statistical test results to baseline are given as *p < 0.05, ***p < 0.005, ****p < 0.0001. No significant differences were seen between sepsis groups.