Changes in arterial blood gas variables, lactate concentration, and lung wet/dry ratio during mechanical ventilation. In blood gas variables and lactate concentration, value are expressed as median. Vertical lines indicate the interquartile range (IQR). In lung wet/dry ratio, boxes extend from the 25th to 75th percentile; the horizontal line shows the median. Error bars show the minimum and maximum. ANP, atrial natriuretic peptide; IRI, ischemia-reperfusion injury (unilateral). **p < 0.01 vs. the IRI + ANP group, ††p < 0.01 vs. the sham + ANP group, ##p < 0.01 vs. the sham + saline group.