Changes in the HR, MAP, and plasma concentrations of creatinine and potassium during spontaneous breathing. Values are expressed as median. Vertical lines indicate the interquartile range (IQR). ANP, atrial natriuretic peptide; HR, heart rate; IRI, ischemia-reperfusion injury (bilateral); LR, lactated Ringer's solution; MAP, mean arterial pressure. *p < 0.05 vs. the IRI + ANP group, #p < 0.05 vs. the sham + LR group.