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Intensive Care Medicine Experimental
Figure 2 | Intensive Care Medicine Experimental

Figure 2

From: Calcium desensitisation in late polymicrobial sepsis is associated with loss of vasopressor sensitivity in a murine model

Figure 2

Sepsis was associated with increased activation state of MLCP. The activity state of MLCP was greater in isolated, unstimulated caudal arteries from 5-day CLP mice than in those from sham mice. The increased activity state of MLCP was indexed by reduction in the ratio of Thr855 phosphorylated to unphosphorylated MYPT determined by Western blot analysis of snap-frozen vessel segments. *p < 0.05, n = 6 to 7.

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