Figure 5From: Calcium desensitisation in late polymicrobial sepsis is associated with loss of vasopressor sensitivity in a murine model The vascular contractile response to the direct PKC activator phorbol-dibutyrate (PDBu) was attenuated in sepsis. Wire myograph-mounted femoral arteries from 5-day CLP mice developed lower tension under stimulation with PDBu (5 μM) compared to those from sham mice. *p < 0.05, n = 8 to 13.Back to article page