Figure 7
Quantitative analysis of CD45 high + cells 24 h after acute brain injury. Area (A), perimeter (B), circularity (C), Feret’s diameter (D), aspect ratio (E), solidity (F), and grid crossings (G) calculated for naïve (striatum and cortex), tMCAo, pMCAo, or TBI mice are shown as box and whiskers with line at mean and min-to-max values. None of these parameters changed across models, in line with the unvaried round-shaped morphology of CD45high+ cells. CD45high+ cell density (H) in the lesion core after pMCAo and TBI was higher compared to tMCAo. One-way ANOVA followed by Tukey’s multiple comparison test, *p < 0.05, ***p < 0.001, n = 6 (n.d. = not detectable).