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Figure 2 | Intensive Care Medicine Experimental

Figure 2

From: Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines

Figure 2

Serial mean changes for HS animals vs. controls. This figure compares the serial mean (±SEM) changes from baseline in fluid in (A), fluid out (B), net fluid (C), pulmonary capillary wedge pressure (PCWP) (D), mean arterial blood pressure (E; MAP), heart rate (F; HR), lactate (G), blood urea nitrogen (H; BUN), creatinine (I), chloride (J), pH (K), and alveolar to arterial oxygen gradient (L; AaO2) for animals challenged with edema toxin and receiving no treatment (maintenance fluid only) versus hemodynamic support alone (HS; fluids and norepinephrine titrated to pulmonary artery wedge pressure and mean arterial blood pressure, respectively) in Study 1. Units of measure are shown in each panel. *p ≤ 0.05, **p < 0.0001.

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