Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome

Intensive Care Medicine Experimental

Table 2 BAL total protein concentration and histological analysis in vehicle and Ang-(1-7) treated groups

Alveolar permeability and histology	Lung	Vehicle	ALD	AHD
Permeability: BAL total protein content
Protein content (μg/ml)	Right	2,454 ± 1,142	2,600 ± 844	2,536 ± 710
Protein content (μg/ml)	Left	1,108 ± 668	1,406 ± 808	1,213 ± 610
Histological analysis
Alveolar serofibrinous exudate	Right	1.4 ± 0.5	2.0 ± 2.7	1.2 ± 0.9
Alveolar serofibrinous exudate	Left	1.0 ± 1.0	1.0 ± 1.0	0.3 ± 0.6
Alveolar hemorrhages	Right	0.7 ± 0.9	0.7 ± 1.1	0.7 ± 1.7
Alveolar hemorrhages	Left	0 ± 0	0 ± 0	0 ± 0
Alveolar inflammatory cells	Right	0.8 ± 0.8	0.4 ± 1.2	0.5 ± 0.8
Alveolar inflammatory cells	Left	0 ± 0	0 ± 0	0 ± 0
Parenchymal necrosis	Right	1.6 ± 3.1	1.2 ± 2.3	1.2 ± 2.6
Parenchymal necrosis	Left	0.3 ± 0.6	0 ± 0	0 ± 0