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Table 1 Hemodynamic and blood gas measurements

From: Alveolar instability (atelectrauma) is not identified by arterial oxygenation predisposing the development of an occult ventilator-induced lung injury

 

BL-uninjured

Post-injury

PEEP 3

PEEP 6

PEEP 9

PEEP 12

PEEP 15

PEEP 18

HR (beats/min)

189.1 ± 59.1

186.4 ± 45.1

204.9 ± 44.5

172.2 ± 51.1

186.0 ± 38.3

176.7 ± 44.6

179.9 ± 61.5

150.5 ± 42.9

MAP (mmHg)

71.8 ± 21.1

61.3 ± 12.6

50.6 ± 16.2

52.5 ± 26.5

49.0 ± 24.1

47.4 ± 18.1*

44.5 ± 16.5*

39.1 ± 15.7*

pH

7.35 ± 0.07

7.246 ± 0.087

7.204 ± 0.049*

7.153 ± 0.101*

7.209 ± 0.066*

7.197 ± 0.109*

7.21 ± 0.15*

7.199 ± 0.195*

PaCO2 (mmHg)

38.11 ± 11.67

53.58 ± 14.43*

47.42 ± 13.21

49.68 ± 11.22

36.49 ± 4.85

35.43 ± 5.99

32.0 ± 7.0

29.39 ± 7.17

PaO2 (mmHg)

467.5 ± 163.5

54.03 ± 24.70*

60.07 ± 13.10*

106.3 ± 90.47*

169.7 ± 143.5*

221.5 ± 115.5*

266.0 ± 122.0*

352.0 ± 159.0

FiO2 (%)

100

100

100

100

100

100

100

100

% Saturation

97.63 ± 1.26

56.43 ± 20.96*

64.76 ± 16.04*

65.12 ± 17.54

88.77 ± 5.74

92.26 ± 8.58

93.15 ± 8.11

95.1 ± 5.98

P/F

507.6

54.03*

60.07*

106.3*

169.7*

221.5*

266.0*

352.0*

  1. *p ≤ 0.05 as compared to baseline (BL)