Fig. 5

Concentrations of proinflammatory cytokines and MPO and activity of NF-κB and HIF-1α in right lung homogenates. a TNF-α, b CXCL-1, and c MPO concentrations and d NF-κB p65 binding activities and e HIF-1α concentrations in right lung homogenates were measured by ELISA and normalized to the total protein concentration. *p < 0.05 compared with the ULV group (n = 5 rats per group). TNF-α tumor necrosis factor α, CXCL-1 chemokine (C-X-C motif) ligand 1, MPO myeloperoxidase, NF-κB nuclear factor-κB, HIF-1 hypoxia-inducible factor 1, ULV unilateral lung ventilation, NTV normal tidal volume