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Table 1 Animals and anaesthesia

From: Successful ECMO-cardiopulmonary resuscitation with the associated post-arrest cardiac dysfunction as demonstrated by MRI

Pig (sus scrofa domestica)

    Strain

Crossbreeding

    Numbers included

8

    Gender

3 female 5 male

    Weight

49.7 ± 2.3 kg

Ventilation

 

    Mode

Volume control

    Tidal volume

10 ml/kg

    PEEP

5 cm H2O

    Respiratory rate

18/min

    I:E ratio

1:2

    FiO2

40 %

Premedication (i.m)

 

    Azaperone

4 ml 40mg/ml (3 mg/kg)

    Ketamine

30 ml 50mg/ml (30 mg/kg)

    Atropine

1 ml 1mg/ml (20 μg/kg)

Anaesthesia (i.v)

 

    Pentobarbital

4 mg/kg/h

    Morphine

2 mg/kg/h

    Midazolam

0.15 mg/kg/h

    Rocuronium

3 mg/kg/h

Euthansia (i.v)

 

    Pentobarbital

20 ml 50 mg/ml (20 mg/kg)

    Morphine

5 ml 10 mg/ml (1 mg/kg)

    Potassium chloride

50 ml 1 mmol/ml (1 mmol/kg)

  1. Animals and anaesthesia used in the experiments
  2. Weight as mean ± standard deviation; PEEP positive end-expiratory pressure, I:E ratio the ratio of inspiratory time (I) to expiratory time (E), FiO 2 fraction of inspired oxygen, i.m. intra muscular, i.v. intra venous