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Fig. 3 | Intensive Care Medicine Experimental

Fig. 3

From: Noradrenalin effectively rescues mice from blast lung injury caused by laser-induced shock waves

Fig. 3

Effects of LISW on heart rate (HR), systolic blood pressure (sBP), peripheral oxyhemoglobin saturation (SpO2), and the shock index in the anesthetized mice. a HR data were recorded immediately before (0 min) and every 5 min up to 60 min after being exposed twice to LISW at 1.2 (LISW low group), 1.3 (LISW medium group; two mice that died within 10 min were excluded), and 1.4 (LISW high group; seven mice that died within 10 min were excluded) J/cm2. Sham mice were not exposed to LISW. p < 0.01 interaction by repeated measures ANOVA, **p < 0.01 for significance for LISW high group vs. LISW low group or Sham group, *p < 0.05 for significance for LISW medium group vs. LISW high group or Sham group determined according to Scheffe’s F test. The data are presented as the mean ± standard error. b sBP was recorded immediately before (0 min) and every 5 min up to 60 min being exposed twice to LISW at 1.2 (LISW low group), 1.3 (LISW medium group; two mice that died within 60 min were excluded), and 1.4 (LISW high group; seven mice that died within 10 min were excluded) J/cm2. Sham mice were not exposed to LISW. p < 0.01 interaction by repeated measures ANOVA, **p < 0.01 for significance for Sham group vs. LISW low group, medium group, or high group determined according to Scheffe’s F test. The data are shown as the mean ± standard error. c SpO2 in the anesthetized mice was assessed immediately before (0 min) and every 5 min up to 60 min after being exposed twice to LISW at 1.2 (LISW low group), 1.3 (LISW medium group; two mice that died within 60 min were excluded), and 1.4 (LISW high group; seven mice that died within 10 min were excluded) J/cm2. Sham mice were not exposed to LISW. p < 0.01 interaction by repeated measures ANOVA, **p < 0.01 for significance for Sham group vs. LISW low group, medium group, or high group determined according to Scheffe’s F test. The data are shown as the mean ± standard error. d The shock index in the anesthetized mice was assessed immediately before (0 min) and every 5 min up to 60 min after being exposed twice to LISW at 1.2 (LISW low group), 1.3 (LISW medium group; two mice that died within 60 min were excluded), and 1.4 (LISW high group; seven mice that died within 10 min were excluded) J/cm2. Sham mice were not exposed to LISW. There were no significant differences between the groups (repeated measures ANOVA). The data are shown as the mean ± standard error

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