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Table 3 Hemodynamic variables

From: Lung anatomy, energy load, and ventilator-induced lung injury

 

End-inspiratory volumes/inspiratory capacity

 

Below

Within

Above

 

First

Last

P

First

Last

P

First

Last

P

No.

29

38

9

CO (L)

2.1 [1.9–2.8]

2.0 [1.6–2.4]

0.277

2.00 [1.70–2.20]

2.10 [1.50–2.80]

0.569

2.40 [2.35–2.45]

2.05 [1.80–2.75]

0.776

Mean arterial blood pressure (mmHg)

86.4 ± 16.1

77.5 ± 16.3

0.084

78.5 ± 12.3

57. 3 ± 16.4

<0.001

74.7 ± 12.2

77.0 ± 24.7

0.823

Mean pulmonary artery pressure (mmHg)

15.8 ± 5.4

17.8 ± 6.3

0.157

19.8 ± 7.8

25.0 ± 9.8

0.005

23.9 ± 3.4

23.7 ± 4.09

0.911

HR (bpm)

97.4 ± 21.3

83.8 ± 26.1

0.026

108.9 ± 34.6

132.6 ± 49.0

0.021

121.8 ± 31.0

127.2 ± 47.1

0.846

SvO2

65.2 ± 8.4

59.8 ± 13.5

0.036

58.0 ± 11.9

48.0 ± 18.7

0.013

57.3 ± 11.2

52.7 ± 8.9

0.372

  1. Mean ± standard deviations or median (interquartile range) of hemodynamic variables at the beginning (FIRST) and end (LAST) of the experiments. Pigs were grouped according to end-inspiratory volume as lower (BELOW), within (WITHIN), or higher (ABOVE) than normal inspiratory capacity. P refers to paired t test or Wilcoxon’s Signed Rank Test, as appropriate. CO indicates cardiac output (available data, 22 below, 26 within, 4 above); mean arterial blood pressure (29 below, 37 within, 6 above); mean pulmonary artery pressure (26 below, 28 within, 5 above)
  2. HR heart rate (27 below, 34 within, 5 above), SvO 2 venous oxygen saturation (29 below, 33 within, 6 above)