Skip to main content

Table 1 Comparison of survival rates in a rat model of histone H3 administration

From: Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction

Group

Histone H3 dose (mg/kg)

25

50

100

No treatment

1/6 (17 %)

0/6 (0 %)

0/6 (0 %)

UFH high-dose

6/6* (100 %)

6/6** (100 %)

4/6 (67 %)

LMWH high-dose

6/6* (100 %)

5/6* (83 %)

4/6 (67 %)

Argatroban high-dose

1/6 (17 %)

1/6 (17 %)

0/6 (0 %)

  1. *p < 0.05; **p < 0.01 compared with no treatment group