Table 2 Biochemical variables obtained from microdialysis
From: A technique for continuous bedside monitoring of global cerebral energy state
Elapsed time (min) | LP ratio | Lactate (mM/L) | Pyruvate (μM/L) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Hemisphere | Sagittal sinus | Femoral | Hemisphere | Sagittal sinus | Femoral | Hemisphere | Sagittal sinus | Femoral | |
S −60 | 15 (14–18) | 13 (9–16) | 11 (11–19) | 20.7 (10.7–30.0) | 20.1 (10.7–20.3) | 10.6 (10.1–1.9) | 131 (107–178) | 111 (106–123) | 141 (99–160) |
S −30 | 13 (11–16) | 13 (6–16) | 12 (10–17) | 2.9 (2.4–3.5) | 2.2 (2.2–2.2) | 2 (1.7–2.6) | 191 (151–205) | 200 (193–371) | 166 (161–175) |
S | 15 (11–18) | 14 (8–26) | 13 (10–21) | 2.4 (2.1–3.1) | 3.4 (2.6–5.2) | 2.2 (1.6–3.4) | 185 (153–210) | 220 (161–388) | 137 (131–153) |
0 | 20 (17–41) | 45 (32–46) | 33 (30–36) | 7.6 (7.2–8.0) | 11.1 (10.5–11.7) | 3 (2.3–4.0) | 110 (107–149) | 178 (144–208) | 181 (129–193) |
30 | 60 (27–117) | 36 (23–63) | 27 (26–27) | 10.3 (7.8–11.0) | 6.8 (4.6–12.1) | 3.8 (3.7–4.4) | 143 (92–163) | 222 (147–230) | 181 (111–187) |
60 | 169 (45–418) | 85 (36–112) | 28 (26–35) | 14.6 (11.8–17.2) | 9 (6.6–13.2) | 5.5 (5.2–6.8) | 85 (43–137) | 219 (128–272) | 214 (144–286) |
90 | 351 (105–774) | 78 (42–117) | 29 (25–33) | 14.9 (10.2–18.8) | 10.2 (7.0–13.6) | 7.8 (4.2–9.3) | 36 (21–49) | 175 (111–208) | 312 (256–348) |
120 | 704 (97–1454) | 94 (63–135) | 29 (25–35) | 12.9 (10.2–17.2) | 9.7 (8.0–12.0) | 9.7 (4.0–12.9) | 28 (9–64) | 129 (68–232) | 305 (191–348) |
150 | 879 (115–1238) | 123 (36–332) | 34 (24–37) | 11.2 (10.6–15.9) | 8.9 (8.0–13.8) | 6.4 (3.0–10.9) | 24 (9–210) | 80 (29–269) | 266 (162–308) |
180 | 724 (264–2479) | 150 (63–308) | 30 (22–34) | 12.9 (9.7–14.6) | 8.8 (6.8–13.1) | 7 (3.5–9.8) | 38 (6–158) | 90 (34–168) | 215 157–274) |
210 | 846 (243–1990) | 309 (103–488) | 27 (21–31) | 13.4 (11.2–13.8) | 9.6 (8.0–14.1) | 4.4 (3.1–7.7) | 8 (2–94) | 81 (15–150) | 192 (171–286) |
Elapsed time (h) | Glucose (mM/L) | Glutamate (μM/L) | Glycerol (μM/L) | ||||||
Hemisphere | Sagittal sinus | Femoral | Hemisphere | Sagittal sinus | Femoral | Hemisphere | Sagittal sinus | Femoral | |
S −01:00 | 2.4 (1.2–3.7) | 3 (1.3–4.0) | 5.2 (3.1–5.3) | 5 (5–13) | 130 (75–168) | 183 (168–200) | 27 (15–50) | 31 (17–57) | 34 (28–54) |
S −00:30 | 2.9 (2.4–3.7) | 2.9 (1.1–3.7) | 4.1 (2.4–7.1) | 8 (3–11) | 162 (121–177) | 199 (159–209) | 26 (14–55) | 28 (24–63) | 34 (26–35) |
S | 3.6 (2.7–4.1) | 1.7 (1.3–3.8) | 3.7 (2.1–6.5 | 6 (4–7) | 174 (104–204) | 180 (148–209) | 23 (13–41) | 31 (23–55) | 21 (20–29) |
0 | 1.7 (1.5–1.9) | – | 1.2 (0.7–1.6) | – | 87 (50–121) | 202 (169–221) | 40 (40–40) | 74 (49–100) | 12 (11–14) |
30 | 1.9 (1.2–2.4) | 1.3 (0.6–4.2) | 6.9 (1.3–9.2) | 19 (4–55) | 158 (84–159) | 185 (163–206) | 56 (32–108) | 53 (37–112) | 21 (8–32) |
60 | 1.0 (0.7–1.4) | 2 (0.02–2.2) | 3.8 (1.1–8.2) | 68 (36–101) | 156 (132–204) | 181 (158–204) | 180 (133–201) | 96 (53–159) | 33 (14–117) |
90 | 0.4 (0.3–0.5) | 0.6 (0.02–1.5) | 5.4 (1.7–7.6) | 119 (119–119) | 225 (204–248) | 172 (149–195) | 329 (254–337) | 120 (102–190) | 89 (29–486) |
120 | 0.2 (1.0–0.3) | 0.3 (0.04–0.7) | 3.4 (1.2–7.3) | 245 (199–291) | 209 (209–209) | 192 (152–198) | 415 (318–455) | 192 (123–258) | 83 (23–671) |
150 | 0.1 (0.1–1.0) | 0.1 (0.02–0.5) | 3.1 (0.5–5.6) | 327 (231–329) | 199 (152–259) | 153 (107–177) | 403 (377–548) | 222 (151–286) | 76 (19–621) |
180 | 0.2 (0.1–1.3) | 0.1 (0.02–0.2) | 1.8 (0.5–5.9) | 335 (289–367) | 198 (133–256) | 173 (139–180) | 382 (333–547) | 213 (191–230) | 71 (18–314) |
210 | 0.3 (0.1–0.9) | 0.02 (0.02–0.7) | 5.5 (0.9–8.1) | 311 (232–322) | 257 (227–287) | 186 (184–188) | 522 (474–612) | 321 (268–331) | 101 (26–182) |