| |
Baseline
|
After haemorrhage
|
Resuscitated
|
|---|
|
MAP (mmHg)
| | | | |
|
FFP
|
82 ± 18
|
53 ± 9
|
68 ± 11
|
*#
|
|
ALB
|
74 ± 20
|
54 ± 12
|
70 ± 10
|
*#
|
|
RA 4.5
|
100 ± 9
|
50 ± 6
|
57 ± 7
| |
|
SHAM
|
84 ± 7
|
100 ± 20
|
90 ± 18
| |
|
ScvO2 (%)
| | | | |
|
FFP
|
82 ± 5
|
40 ± 9
|
75 ± 7
|
*
|
|
ALB
|
78 ± 11
|
44 ± 14
|
74 ± 9
|
*
|
|
RA 4.5
|
85 ± 3
|
46 ± 9
|
65 ± 11
|
*
|
|
SHAM
|
82 ± 7
|
75 ± 5
|
76 ± 8
| |
|
Lactate (mmol/L)
| | | | |
|
FFP
|
2.2 ± 0.5
|
6.0 ± 1.9
|
1.8 ± 0.7
|
*
|
|
ALB
|
2.2 ± 0.5
|
6.5 ± 3.3
|
1.2 ± 0.5
|
*#
|
|
RA 4.5
|
2.0 ± 0.7
|
5.4 ± 1.1
|
2.4 ± 1.4
|
*
|
|
SHAM
|
1.8 ± 0.3
|
2.1 ± 1.1
|
1.8 ± 0.2
| |
|
Base excess (mmol/L)
| | | | |
|
FFP
|
5.1 ± 1.2
|
−3.9 ± 3.8
|
5.9 ± 1.0
|
*†
|
|
ALB
|
5.1 ± 1.4
|
−4.4 ± 6.4
|
0.9 ± 1.8
| |
|
RA 4.5
|
5.4 ± 1.4
|
−2.8 ± 2.6
|
0.3 ± 2.2
| |
|
SHAM
|
6.0 ± 1.
|
3.2 ± 1.6
|
2.2 ± 2.2
| |
|
Haematocrit (%)
| | | | |
|
FFP
|
42 ± 1
|
33 ± 3
|
19 ± 2
|
*
|
|
ALB
|
42 ± 3
|
33 ± 5
|
18 ± 3
|
*
|
|
RA 4.5
|
42 ± 1
|
31 ± 5
|
20 ± 3
|
*
|
|
SHAM
|
42 ± 1
|
39 ± 4
|
40 ± 6
| |
- Data presented as mean ± SD. The change in values after resuscitation compared to after haemorrhage within groups was evaluated with paired t test corrected for multiple analyses with the Bonferroni correction (*P < 0.05). Differences in between groups after resuscitation was analysed with one-way repeated measurement ANOVA followed by post hoc testing using the Newman-Keuls correction
-
MAP mean arterial pressure, ScvO
2
central venous oxygen saturation, FFP fresh frozen plasma, ALB albumin, RA Ringer’s acetate
-
#Significant difference compared to the RA group
-
†Significant difference compared to ALB and RA groups, P < 0.05
