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Table 1 Comparison of biomarkers for predicting RIFLE I/F

From: Cross-species validation of cell cycle arrest markers for acute kidney injury in the rat during sepsis

Biomarker

No AKI

AKI

p value

AUC

[TIMP-2]·[IGFBP7] (μg2/mL2)

0.019 ± 0.001

0.039 ± 0.003

<0.0001

0.89 (0.80–0.98)

Urine NGAL (IU/mL)

2157.6 ± 102.4

2472.8 ± 123

0.04

0.71 (0.63–0.80)

Plasma NGAL (IU/mL)

2143.3 ± 29.6

2077 ± 44.5

0.21

0.62 (0.46–0.79)

Urine cystatin C (IU/mL)

1609.8 ± 284.6

2572.8 ± 353.6

0.03

0.75 (0.56–0.93)

Plasma cystatin C (IU/mL)

1027.3 ± 185.8

2344.9 ± 462.5

<0.01

0.78 (0.65–0.90)

  1. All comparisons are for the post-resuscitation (primary) time point. Shown are means ± standard error and areas under the receiver operating characteristic curves (AUC) with 95 % confidence intervals. P values are for two-sided t test