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Table 1 Comparison of biomarkers for predicting RIFLE I/F

From: Cross-species validation of cell cycle arrest markers for acute kidney injury in the rat during sepsis

Biomarker No AKI AKI p value AUC
[TIMP-2]·[IGFBP7] (μg2/mL2) 0.019 ± 0.001 0.039 ± 0.003 <0.0001 0.89 (0.80–0.98)
Urine NGAL (IU/mL) 2157.6 ± 102.4 2472.8 ± 123 0.04 0.71 (0.63–0.80)
Plasma NGAL (IU/mL) 2143.3 ± 29.6 2077 ± 44.5 0.21 0.62 (0.46–0.79)
Urine cystatin C (IU/mL) 1609.8 ± 284.6 2572.8 ± 353.6 0.03 0.75 (0.56–0.93)
Plasma cystatin C (IU/mL) 1027.3 ± 185.8 2344.9 ± 462.5 <0.01 0.78 (0.65–0.90)
  1. All comparisons are for the post-resuscitation (primary) time point. Shown are means ± standard error and areas under the receiver operating characteristic curves (AUC) with 95 % confidence intervals. P values are for two-sided t test