Fig. 7

Immunohistochemical pictures of the colocalization of neutrophil granulocytes and ICAM-1 in the cortex (a–e) and magnifications from the cortex (f–h) and the SFO and neighboring choroid plexus (i–k). LPS increased the number of neutrophil granulocytes (green) that were colocalized with ICAM-1 (red) in the cortex which was prevented by vagus nerve stimulation (for quantification see Fig. 8). Pictures g–h and j–k show representative magnifications of this colocalization in the cortex and the SFO and neighboring choroid plexus of LPS-stimulated animals. Similar pictures could be observed in all the experimental groups. The scale bar in picture b represents 200 μm and applies to the pictures b–e. The scale bar in picture g and h represents 25 μm; the one in picture j 50 μm and the one in picture k 25 μm, respectively