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Table 1 Group-averaged data for blood glucose, lactate, arterial pH, pO2, and pCO2

From: Modulatory effects of vagal stimulation on neurophysiological parameters and the cellular immune response in the rat brain during systemic inflammation

 

Glucose (mg/dl)

Lactate (mmol/l)

pH

pO2 (mmHg)

pCO2 (mmHg)

 

Baseline

End

Baseline

End

Baseline

End

Baseline

End

Baseline

End

SHAM

82 ± 27

71 ± 13

1.3 ± 0.7

1.0 ± 1.0

7.50 ± 0.03

7.49 ± 0.04

252 ± 26

223 ± 16

35 ± 4

35 ± 2

SHAM + LPS

84 ± 26

72 ± 18

1.2 ± 0.6

5.1 ± 1.3***

7.49 ± 0.05

7.42 ± 0.04***

239 ± 16

214 ± 17

37 ± 3

36 ± 3

LPS + VGX

98 ± 20

75 ± 17

1.2 ± 0.7

4.9 ± 1.5***

7.48 ± 0.03

7.42 ± 0.05***

249 ± 17

223 ± 14

38 ± 4

34 ± 2

LPS + VGX + VNS

95 ± 24

79 ± 22

1.2 ± 0.5

3.9 ± 0.9***#$

7.49 ± 0.03

7.43 ± 0.04***

242 ± 24

220 ± 26

36 ± 5

36 ± 3$

  1. Data are given as means ± standard deviation (SD) (n = 15) together with statistical differences. Significance is given as: ***P < 0.001; # compared with SHAM + LPS, # P < 0.05; $ compared with LPS + VGX, $ P < 0.05
  2. LPS lipopolysaccharide, pO 2 partial pressure of oxygen, pCO 2  partial pressure of carbon dioxide, SHAM sham surgery, VGX bilateral vagotomy, VGX + VNS bilateral vagotomy and distal vagus nerve stimulation