Table 2 Respiratory rates of isolated mitochondria and permeabilized fibers after incubation with plasma

Isolated mitochondria

State 3 (nmol O₂ × U CS⁻¹ × min⁻¹)

State 4 (nmol O₂ × U CS⁻¹ × min⁻¹)

RCR

 Septic 30 min

20.6 ± 6.2

2.1 ± 1.1

11.0 ± 3.5

 Post-op 30 min

20.7 ± 8.4

2.0 ± 1.1

11.0 ± 2.4

Permeabilized fibers

State 3 (nmol O₂ × min⁻¹ × mg w.w⁻¹)

State 2 (nmol O₂ × min⁻¹ × mg w.w⁻¹)

RCR

 Control fibers

2.9 ± 0.7

0.27 ± 0.04

11.2 ± 2.3

 Healthy 30 min

2.4 ± 0.7

0.25 ± 0.06

9.5 ± 2.0

 Septic 30 min

2.6 ± 0.3

0.30 ± 0.07

8.8 ± 1.5

 Healthy 120 min

2.5 ± 0.6

0.28 ± 0.13

10.2 ± 3.2

 Septic 120 min

2.5 ± 0.4

0.27 ± 0.06

9.5 ± 2.2