Fig. 1

a Metabolic pathways of circulating leukocytes from non-hypoxic critically ill patients. Data inside the parentheses indicates the total number of genes (denominator) included in pathway analysis and the number of genes (numerator) that were statistically significantly different between critically ill patients and healthy controls. b Heat map of the glycolysis pathway. Each row represents a gene, and each column represents a sample. Red colour denotes up-regulation, and blue colour denotes down-regulation. For critically ill patients, the study period was 5 days. For healthy volunteers, the study period was 7 days. c Heat map of the tricarboxylic acid pathway. Each row represents a gene, and each column represents a sample. Red colour denotes up-regulation and blue colour denotes down-regulation. For critically ill patients, the study period was 5 days. For healthy volunteers, the study period was 7 days