Skip to main content
Fig. 6 | Intensive Care Medicine Experimental

Fig. 6

From: Heparin-binding protein is important for vascular leak in sepsis

Fig. 6

Unfractionated heparin blocked HBP-induced permeability increases. EA.hy926 cells were grown to confluence on permeable supports and stimulated with 10 μg/mL HBP, pre-incubated with the indicated dose of heparin. a TEER was measured 1.5 h after stimulation and is normalized to empty inserts. b HRP was also added to the top chamber, and HRP passage was measured 2 h after stimulation. Error bars are standard error of the mean, n = 3 for each condition. One-way ANOVA with Dunnett’s test for multiple comparisons was used to compare each group to the condition with HBP and no heparin (far left).*P < 0.05, **P < 0.01, ***P < 0.001

Back to article page