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Fig. 3 | Intensive Care Medicine Experimental

Fig. 3

From: Plasmadiafiltration ameliorating gut mucosal barrier dysfunction and improving survival in porcine sepsis models

Fig. 3

Immunohistochemical localization of zonula occludens (ZO)-1 (b) and occludin (a) in the ileum tissue from cecal ligation puncture (CLP) porcines. A more regular distribution pattern of ZO-1 and occludin (see arrow) along the epithelium was found in PDF animals. Contrastingly, a significant disruption of immunosignal for them was observed along the epithelium in HVHF (see arrow) and control group, particularly for control animals; almost all-normal construction disappeared and infiltrated with a lot of inflammatory cells. p < 0. 01 PDF group vs. HVHF group, or control group, respectively. IOD immunochemistry optical density

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