Table 1 Evolution of systemic and renal hemodynamics parameters during the experiment

 Time control

102 ± 9.0

86.3 ± 13.4

80.1 ± 8.8

76.8 ± 9.3

 Control + NAC

87.7 ± 7.6

75.3 ± 10.5

70.5 ± 8.0

57.3 ± 5.6***

 LPS

101 ± 11.1

56.8 ± 10.5***

53.7 ± 9.4***

45.8 ± 7.9***

 LPS + HES-RA

92.1 ± 8.7

55.6 ± 9.5***

65.5 ± 4.9 * ^{, +}

51.6 ± 3.7***

 LPS + HES-RA + NAC

98.8 ± 8.7

49.8 ± 8.5***

64.1 ± 4.7**

52.6 ± 6.1***

 Time control

5.4 ± 0.6

4.8 ± 0.8

5.3 ± 0.9

4.5 ± 1.5

 Control + NAC

5.7 ± 0.7

4.3 ± 0.9

4.8 ± 1.5

4 ± 1.1

 LPS

5.7 ± 1.4

1.3 ± 0.7***

1.4 ± 0.5***

0.7 ± 0.6***

 LPS + HES-RA

6.6 ± 0.3

1.9 ± 1.5***

5.6 ± 1.8 ⁺⁺⁺

5.0 ± 0.4 ⁺⁺⁺

 LPS + HES-RA + NAC

5.5 ± 0.4

1 ± 0.4***

3.5 ± 0.9*^{, ++}

4.8 ± 2.2 ⁺⁺⁺

 Time control

1910.2 ± 260.5

1793.7 ± 227.4

1524.3 ± 188.2

1861.3 ± 751.2

 Control + NAC

1548.6 ± 249.2

1782.6 ± 368.6

1606.7 ± 583.2

1521.9 ± 511.1

 LPS

1774.8 ± 302.4

5911.5 ± 3333.4***

4182.9 ± 829.7*

10,372 ± 5182.2 ***

 LPS + HES-RA

1410 ± 152.2

3293.2 ± 1978.9 ⁺

1130.2 ± 348.1 ⁺⁺

1004.3 ± 48.3 ⁺⁺⁺

 LPS + HES-RA + NAC

1787.2 ± 236

5795.8 ± 2517.4***

1909.8 ± 375.7

1199.1 ± 318.3 ⁺⁺⁺