Parameter | Group | T0 | T2 | T4 | Time effect | Group effect | Interaction | |
---|---|---|---|---|---|---|---|---|
V T (mL.kg−1) | Control | PCV | 5.9 ± 0.4 | 5.7 ± 0.5 | 5.7 ± 0.5 | ns | ns | ns |
PSV | 6.5 ± 0.9 | 6.6 ± 1.0 | 6.6 ± 0.7 | |||||
Emphysema | PCV | 6.0 ± 1.0 | 5.9 ± 0.6 | 6.1 ± 0.5 | ||||
PSV | 6.1 ± 1.1 | 6.3 ± 1.1 | 6.3 ± 1.1 | |||||
RR (breaths.min−1) | Control | PCV | 62.1 ± 4.7 | 62.1 ± 4.6 | 62.2 ± 4.5 | p < 0.05 | p < 0.001 | p < 0.05 |
PSV | 39.8 ± 4.9* | 44.9 ± 5.6* | 54.6 ± 12.7 | |||||
Emphysema | PCV | 59.5 ± 4.0 | 60.8 ± 2.9 | 59.8 ± 3.5 | ||||
PSV | 56.7 ± 10.8** | 52.9 ± 7.8 | 62.0 ± 11.0 | |||||
Ti/Ttot (s) | Control | PCV | 0.35 ± 0.00 | 0.35 ± 0.01 | 0.35 ± 0.00 | ns | p < 0.05 | ns |
PSV | 0.31 ± 0.10 | 0.31 ± 0.07 | 0.32 ± 0.05 | |||||
Emphysema | PCV | 0.35 ± 0.00 | 0.35 ± 0.00 | 0.35 ± 0.01 | ||||
PSV | 0.29 ± 0.05 | 0.27 ± 0.02*** | 0.31 ± 0.06 | |||||
Ppeak,L (cmH2O) | Control | PCV | 10.8 ± 1.9 | 11.2 ± 1.5 | 12.1 ± 1.4 | ns | p < 0.01 | p < 0.05 |
PSV | 12.6 ± 1.8 | 13.0 ± 2.2 | 12.3 ± 3.1 | |||||
Emphysema | PCV | 11.3 ± 1.5 | 12.2 ± 1.5 | 13.5 ± 1.3 | ||||
PSV | 15.9 ± 2.0**, *** | 15.7 ± 1.7 | 14.3 ± 2.3 | |||||
Pmean,L (cmH2O) | Control | PCV | 5.8 ± 0.7 | 5.8 ± 06 | 6.3 ± 0.4 | p < 0.05 | p < 0.001 | ns |
PSV | 4.8 ± 0.6 | 5.1 ± 0.6 | 5.0 ± 0.7* | |||||
Emphysema | PCV | 5.9 ± 0.6 | 6.2 ± 0.6 | 6.7 ± 0.4 | ||||
PSV | 5.8 ± 0.6** | 5.5 ± 0.4 | 5.3 ± 0.5*** | |||||
PTP/min (cmH2O.s.min−1) | Control | PCV | – | – | – | ns | ns | ns |
PSV | 13.9 ± 13.3 | 14.8 ± 12.5 | 17.5 ± 17.8 | |||||
Emphysema | PCV | – | – | – | ||||
PSV | 18.5 ± 15.0 | 14.9 ± 13.5 | 30.4 ± 14.3 | |||||
P 0.1 (cmH2O) | Control | PCV | – | – | – | ns | ns | ns |
PSV | −1.03 ± 0.93 | −1.25 ± 0.90 | −1.48 ± 0.83 | |||||
Emphysema | PCV | – | – | – | ||||
PSV | −1.47 ± 0.97 | −1.47 ± 1.20 | −2.49 ± 1.41 | |||||
CV of V T (%) | Control | PCV | 0.8 ± 0.6 | 2.1 ± 1.8 | 2.7 ± 3.7 | ns | p < 0.0001 | ns |
PSV | 6.4 ± 3.9 | 8.0 ± 4.6* | 9.5 ± 3.5* | |||||
Emphysema | PCV | 1.9 ± 1.5 | 2.2 ± 1.5 | 2.4 ± 1.6 | ||||
PSV | 6.0 ± 3.1 | 7.2 ± 4.5 | 7.7 ± 7.3 | |||||
CV of RR (%) | Control | PCV | 0.7 ± 0.0 | 1.3 ± 0.0 | 2.4 ± 0.0 | ns | p < 0.001 | ns |
PSV | 49.5 ± 0.3* | 48.0 ± 0.4* | 34.7 ± 0.2* | |||||
Emphysema | PCV | 0.6 ± 0.0 | 0.6 ± 0.0 | 1.3 ± 0.0 | ||||
PSV | 21.0 ± 0.2**, *** | 20.9 ± 0.1**, *** | 18.4 ± 0.1**, *** | |||||
CV of Ti/Ttot (%) | Control | PCV | 1.3 ± 0.5 | 1.6 ± 0.7 | 1.8 ± 0.7 | ns | p < 0.0001 | ns |
PSV | 30.0 ± 7.7* | 27.6 ± 11.3* | 24.1 ± 8.7* | |||||
Emphysema | PCV | 0.9 ± 0.3 | 1.3 ± 0.6 | 1.6 ± 0.9 | ||||
PSV | 17.0 ± 9.7**, *** | 20.2 ± 10.2*** | 18.8 ± 7.1*** |