Skip to main content

Table 1 Respiratory and microcirculatory data for model 1 (intravenous O2 administration)

From: Exploring alternative routes for oxygen administration

  Baseline 60 min 120 min 180 min 240 min
Respiratory rate (n/min)
 IV-O2 65 [62–73] 71 [69–77] 75 [71–83]* 75 [71–81]* 72 [69–79]
 Controls 77 [60–89] 83 [67–96] 81 [69–94] 85 [69–93] 84 [69–97]
PaCO2 (kPa)
 IV-O2 4.8 ± 0.1 3.8 ± 0.1** 3.5 ± 0.1** 3.5 ± 0.1** 3.3 ± 0.1**
 Controls 4.8 ± 0.1 3.5 ± 0.1** 3.4 ± 0.2** 3.2 ± 0.1** 3.1 ± 0.1**
pH
 IV-O2 7.44 ± 0.01 7.52 ± 0.01** 7.53 ± 0.01** 7.53 ± 0.02** 7.53 ± 0.02**
 Controls 7.47 ± 0.01 7.55 ± 0.01** 7.56 ± 0.01** 7.57 ± 0.01** 7.57 ± 0.01**
Perfused vessel density (mm/mm2)
 IV-O2 17.0 ± 0.7 19.5 ± 1.0*** 18.5 ± 0.6 18.6 ± 0.4 18.5 ± 0.8
 Controls 20.9 ± 0.7 24.6 ± 2.1 21.8 ± 1.0 20.8 ± 1.7 20.2 ± 0.9
  1. *p < 0.01; **p < 0.001 versus baseline; ***p < 0.05 versus controls