Table 1 Respiratory and microcirculatory data for model 1 (intravenous O2 administration)
From: Exploring alternative routes for oxygen administration
Baseline | 60 min | 120 min | 180 min | 240 min | |
|---|---|---|---|---|---|
Respiratory rate (n/min) | |||||
IV-O2 | 65 [62–73] | 71 [69–77] | 75 [71–83]* | 75 [71–81]* | 72 [69–79] |
Controls | 77 [60–89] | 83 [67–96] | 81 [69–94] | 85 [69–93] | 84 [69–97] |
PaCO2 (kPa) | |||||
IV-O2 | 4.8 ± 0.1 | 3.8 ± 0.1** | 3.5 ± 0.1** | 3.5 ± 0.1** | 3.3 ± 0.1** |
Controls | 4.8 ± 0.1 | 3.5 ± 0.1** | 3.4 ± 0.2** | 3.2 ± 0.1** | 3.1 ± 0.1** |
pH | |||||
IV-O2 | 7.44 ± 0.01 | 7.52 ± 0.01** | 7.53 ± 0.01** | 7.53 ± 0.02** | 7.53 ± 0.02** |
Controls | 7.47 ± 0.01 | 7.55 ± 0.01** | 7.56 ± 0.01** | 7.57 ± 0.01** | 7.57 ± 0.01** |
Perfused vessel density (mm/mm2) | |||||
IV-O2 | 17.0 ± 0.7 | 19.5 ± 1.0*** | 18.5 ± 0.6 | 18.6 ± 0.4 | 18.5 ± 0.8 |
Controls | 20.9 ± 0.7 | 24.6 ± 2.1 | 21.8 ± 1.0 | 20.8 ± 1.7 | 20.2 ± 0.9 |